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The production of certain peptides produced by the endocrine part of the pancreas is controlled by short-chain fatty acids, such as butyrate, produced in the gut microbiome
This change would abruptly disrupt care for patients who are benefiting from GLP-1s
Table 1 Animal data on fetal effects of maternal GLP-1 agonist exposure
Changes in the gut microbiome are seen in pancreatitis patients when compared to a healthy control group
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